Erectile dysfunction (ED) affects millions of men worldwide, impacting their sexual health and overall quality of life. With various treatment options available, understanding the differences between ED medications is crucial for making an informed decision. This guide explores four main ED drugs – Sildenafil, Tadalafil, Vardenafil, and Avanafil – detailing their mechanisms and benefits. Let’s dive into what Sildenafil, Tadalafil, Sildenafil-Citrate and Vardenafil are, and why Dapoxetine is added to Sildenafil Citrate.

Contents:
Quick Overview of Common ED Drugs
ED Drugs: Mechanism of Action
Sildenafil
Tadalafil
Vardenafil
Avanafil
Sildenafil with Dapoxetine
Comparing different ED Medications
Choosing the Right ED Medication
Links to Relevant Studies

 

ED medications primarily work by improving blood flow to the penis, aiding in gaining and maintaining an erection. Here’s a brief look at the four main types:

  • Sildenafil (Kamagra, Viagra): Known for its rapid onset and effectiveness.
  • Tadalafil (Apcalis, Tadalis, Cialis): Famous for its long-lasting effects and flexibility.
  • Vardenafil (Valif, Levitra): Offers a reliable profile with a balanced onset and duration.
  • Avanafil (Stendra): Noted for its quick action and minimal side effects.

Each medication has unique properties, making them suitable for different preferences and needs.

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ED medications generally enhance erectile function by blocking the enzyme phosphodiesterase type 5 (PDE5).

Inhibition of PDE5: This enzyme normally breaks down cyclic GMP, a substance that relaxes smooth muscles in the penis and increases blood flow. By inhibiting PDE5, these drugs prevent the breakdown of cyclic GMP, thus allowing more blood to flow into the penis and facilitating an erection. This mechanism is fundamental to understanding how different medications affect erectile function.

ED Meds Compared: Sildenafil, Tadalafil, Vardenafil | Ajanta

Sildenafil, marketed as Viagra, was the first ED medication approved by the FDA and remains a popular choice due to its proven effectiveness.

– Mechanism of action: Sildenafil selectively inhibits PDE5, increasing cyclic GMP levels and enhancing blood flow to the penis.

– Dosage and administration: The typical starting dose is 50 mg, taken about an hour before sexual activity. The maximum recommended dose is 100 mg per day.

– Side effects: Common side effects include headaches, flushing, indigestion and nasal congestion. Rare side effects can include vision changes and prolonged erections.

– Ideal candidate: Sildenafil is ideal for men seeking a medication with a quick onset.

 

Sildenafil Kamagra

An alternative to Viagra, Kamagra offers similar effectiveness at a more affordable price. Available in various forms, including tablets and oral jelly, Kamagra provides flexibility and convenience. Discover the key differences between Kamagra and Viagra in our latest blog post to find out which option might be right for you!

Kamagra Oral Jelly: This variant is especially noted for its rapid absorption and ease of use, making it a popular choice for those seeking a quicker onset and more convenient administration.

At AjantaStore you can find the following ED treatment with sildenafil as active ingredient: Kamagra Oral Jelly, Kamagra Polo, Lovegra Oral Jelly, Kamagra Tablets, Kamagra Effervescent Tablets.

 

Sildenafil vs. Sildenafil Citrate

The main difference between those two lies in the terminology. Sildenafil Citrate is the chemical name for Sildenafil which refers to the drug itself. Both terms are used to describe the same effective medication for treating ED.

 

Tadalafil, sold under the brand name Cialis, is renowned for its long duration of action, providing up to 36 hours of effectiveness.

– Mechanism of action: Like Sildenafil, Tadalafil inhibits PDE5, but its extended action allows for longer periods of spontaneity.

– Dosage and administration: For as-needed use, the typical dose is 10 mg, taken at least 30 minutes before sexual activity. For daily use, a lower dose of 2.5 mg to 5 mg is recommended.

– Side effects: Common side effects include back pain, muscle aches, and flushing. Serious side effects are rare but may include changes in vision and hearing.

– Ideal candidate: Tadalafil is best for men who prefer a medication with a longer duration of action with more flexibility in timing.

Discover the essentials of Tadalafil with our comprehensive “Tadalafil 101” blog post – your guide to understanding this powerful medication and its benefits!

Apcalis and Tadalis

Tadalis is a brand of Tadalafil offering the same long-lasting effects as Cialis, often at a lower cost. It provides flexibility with dosing options and effectiveness. Another Tadalafil alternative, Apcalis is available in tablet and oral jelly form and offers similar efficacy and duration. It is well-regarded for its reliability and affordability.

Check out these products: Tadalis and Apcalis Jelly.

 

Vardenafil, known as Levitra, is praised for its balanced profile of effectiveness and duration, making it a reliable choice for many men.

– Mechanism of action: Vardenafil inhibits PDE5, similar to Sildenafil, but may be more selective, potentially offering fewer side effects.

– Dosage and administration: The usual starting dose is 10 mg, taken about an hour before sexual activity. Depending on response and tolerance, the dose can be increased to a maximum of 20 mg per day.

– Side effects: Common side effects include headaches, flushing, and nasal congestion. Rarely, it may cause vision changes or prolonged erections.

– Ideal candidate: Vardenafil is suitable for men who need a reliable medication with potentially fewer side effects.

For more information on Vardenafil, check out our article exploring the uses and benefits of Vardenafil in treating erectile dysfunction.

 

Valif Oral Jelly

A great and effective alternative to traditional Levitra tablets, Valif Oral Jelly provides a rapid onset of action. This form of Vardenafil is convenient and fast-acting, making it an excellent choice for those seeking a quick solution.

 

Avanafil, branded as Stendra, is one of the newer ED medications, known for its rapid onset and minimal side effects.

– Mechanism of action: Avanafil blocks PDE5, like other ED medications, but is designed for faster absorption and quicker action.

– Dosage and administration: The typical starting dose is 100 mg, taken 15 to 30 minutes before sexual activity. The dose can be adjusted up to a maximum of 200 mg per day.

– Side effects: Common side effects include headache, flushing, and nasal congestion. Severe side effects are rare but can include priapism and severe allergic reactions.

– Ideal candidate: Avanafil is ideal for men who require a medication with a very rapid onset and fewer side effects.

 

Dapoxetine is an active ingredient added to Sildenafil Citrate in certain medications, such as Super Kamagra or Priligy. This combination treats both ED and premature ejaculation. The idea is that Dapoxetine helps increase the time before ejaculation, which can enhance the sexual experience. This provides a more comprehensive approach to treatment, which can be beneficial for men dealing with both issues simultaneously.

Examples of products with Dapoxetine: Super Kamagra Jelly and Super Kamagra Tablet.

 

 Sildenafil vs. Tadalafil

  • Effectiveness: Both medications are effective, but Sildenafil typically works within 30-60 minutes, whereas Tadalafil may take longer to take effect.
  • Duration: Sildenafil’s effects last about 4-6 hours, while Tadalafil offers up to 36 hours of effectiveness.
  • Side Effects: Both can cause headaches and flushing; however, Tadalafil may be associated with muscle pain more frequently.

 

Vardenafil vs. Sildenafil

  • Onset of action: Vardenafil may work slightly faster than Sildenafil in some cases.
  • Duration: Both medications offer similar durations of effectiveness, typically 4-6 hours.
  • Side Effects: Vardenafil might have a lower incidence of visual disturbances compared to Sildenafil.

ED Meds Compared: Sildenafil, Tadalafil, Vardenafil | Ajanta

Selecting the best ED medication involves several considerations:

  1. Consultation with a healthcare provider. Always discuss your options with a healthcare provider to find the most suitable medication based on your health profile and needs.
  2. Personal preferences and health conditions. For those seeking spontaneity, Tadalafil might be preferred due to its extended duration. If rapid action is essential, Avanafil or Vardenafil may be better options.
  3. Trial and adjustment. Finding the right medication may require some trial and adjustment. Start with a lower dose and make adjustments as needed under medical supervision.

Wondering how much sildenafil is right for you? Check out our blog post ‘Finding the Right Dose: How Many mg of Sildenafil is Best for You‘ to learn more!

Understanding the differences between ED medications can greatly impact your treatment experience. Sildenafil, Tadalafil, Vardenafil and Avanafil each offer distinct advantages, catering to various needs and preferences. For those seeking to purchase these medications, AjantaStore pharmacy offers a wide selection along with professional advice to help you make the best choice for your situation.

Visit our chemist warehouse today to find the right ED medication for you and take the first step towards enhancing your sexual health and overall well-being.

 

  1. Phosphodiesterase type 5 inhibitors as a treatment for erectile dysfunction: Current information and new horizons
  2. Selectivity of avanafil, a PDE5 inhibitor for the treatment of erectile dysfunction: implications for clinical safety and improved tolerability
  3. Emerging treatments for premature ejaculation: focus on dapoxetine
  4. A comparison of the available phosphodiesterase-5 inhibitors in the treatment of erectile dysfunction
  5. Tadalafil in the treatment of erectile dysfunction
  6. Phosphodiesterase Type-5 Inhibitor Prescription Patterns in the United States Among Men with Erectile Dysfunction: An Update
  7. Vardenafil for the treatment of erectile dysfunction: an overview of the clinical evidence